Nerve Grafting Processes

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Recent advancements in the University School of Medicine located in Kyoto have discovered that adult stem cells do show a propensity to develop into immature Schwann cells within the controlled environment of biochemical nutrient feeding and oxygen supply.
This study will enable continued research into the use of culturing a variety of cells and transplanting them into damaged nerve areas. These artificial nerves hold the hope of surviving nerve grafting with the potential of regeneration of nerve axons that will hold enough vascular tissue and length to bridge nerve synapse gaps.

One of the main deterrents currently experienced in this arena is the rate of rejection by the host to the transplanted cells. While this is a widely known issue with organ transplants, it broaches a wider scope within at the cellular level as well. Currently, focus is attached to processes that will decrease the incidence of transplant cell rejection by the host cell when under transplant techniques of allologous transplant processes. Self transplantation, in other words, "autologous cell transplants" provided by the host, have been the “Gold Standard” up until this time, because the body tends not to reject its own tissue. A severe limitation to this kind of process is the availability of the host's own cells.

As techniques continue to improve, a future for allologous cell transplantation will be successful. Antibiotic research currently being conducted by laboratories will be sure to decrease the incidence of transplant rejection and enable nerve, muscle, and other types of tissue regeneration in the near future.

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